The Best Medicine For Anxiety Disorders SSRIs (selective serotonin reuptake inhibitors) and SNRIs like citalopram (Celexa), Escitalopram (Lexapro), the fluoxetine (Prozac), duloxetine (Cymbalta) and Venlafaxine (Effexor XR) are considered to be the first-line treatment for anxiety disorders. Psychotherapy and exercise are essential for those with anxiety. Antihistamines, such as hydroxyzine
